A cytotoxic safety cabinet, also known as a chemotherapy safety cabinet, is an essential piece of equipment in cancer hospitals, specifically designed to safely handle and mix cytotoxic drugs used in chemotherapy. These cabinets are critical for protecting healthcare workers from the harmful effects of chemotherapy agents, which can be toxic if inhaled or come into contact with the skin. They are designed to provide an enclosed workspace with filtered airflow, usually employing a HEPA filter to remove airborne contaminants. The cabinet maintains a negative pressure environment, ensuring that any potential fumes or particles are directed away from the user and filtered before being released into the room. In addition to providing a sterile working area, these cabinets are built with ergonomic features to enhance user safety and comfort during the preparation of chemotherapy drugs. Their use is vital in reducing the risk of exposure to hazardous drugs, ensuring both the safety of healthcare providers and the effective treatment of cancer patients. In the government sector, the National Institute of Cancer Research and Hospital (NICRH) is the only facility equipped with this specialized safety cabinet.